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In addition to glucose, mammalian spermatozoa actively utilize fatty acid (lipids) as energy source for their motility and metabolism. In ovine spermatozoa endogenous fatty acids have been shown to support the respiration in the absence of glycolytic substrates (Hartee and Mann, 1961). So, fatty acid oxidation may be important to meet the energy requirement of spermatozoa during storage. Free fatty acid may be obtained from lipolysis of stored fat by the enzyme, hormone sensitive lipase (Zechner et al., 2005). L-carnitine is required for the transport of free fatty acids to mitochondria where beta-oxidation occurs for energy production (REF). ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Revised Text: In addition to glucose, mammalian spermatozoa actively utilizes fatty acid (lipids) as an energy source for their motility and metabolism. In ovine spermatozoa, endogenous fatty acids have been shown to support respiration in the absence of glycolytic substrates (Hartee and Mann, 1961). So, fatty acid oxidation may be important to meet the energy requirements of spermatozoa during storage. Free fatty acid may be obtained from lipolysis of stored fat by the enzyme, Hormone Sensitive Lipase (Zechner et al., 2005). L-carnitine is required for the transport of free fatty acids to mitochondria, where beta-oxidation occurs for energy production (REF). Editor: 1. Please review the text carefully to ensure your intended meaning was not mistakenly changed. 2. Before you leave this page, please take a moment to use the "Click here to post comments." link at the bottom of the page to rate the proofreading and leave a comment if you wish. Proofreading and editing pages that receive ratings and comments are moved to the top of the list. |